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The past and present of medical silicone oil: an all-round lubrication assistant for medical equipment

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Silicone oil, as a type of polymer with a unique chemical structure, was born from the booming development of organosilicon chemistry in the 20th century. Initially, silicone oil was just a novel compound studied by chemists in the laboratory. With its special molecular chain structure - silicon-oxygen bond (Si-O) as the main body, it shows stability, low surface tension and excellent temperature resistance that are different from traditional organic compounds.
With the gradual expansion of materials science, researchers began to explore the potential applications of silicone oil in different fields. In the medical field, the early prototypes of medical silicone oil were mainly used for some simple medical device surface treatments, using its low friction properties to reduce the resistance when the device contacts the human tissue and improve the smoothness of the operation. For example, in some early catheter designs, a small amount of silicone oil was tried to reduce the irritation to the urethra during the insertion process.

Development history: Technological innovation promotes medical expansion
1. Material performance optimization: From the mid-to-late 20th century, major breakthroughs were made in organosilicon chemical synthesis technology, which greatly improved the purity and controllability of the molecular structure of silicone oil. Researchers can accurately adjust the molecular weight, functional group type and distribution of silicone oil to prepare a series of silicone oil products with different properties. This progress has laid the foundation for the application of medical silicone oil in more complex medical scenarios. High-purity, low-impurity silicone oil began to be used in ophthalmic surgery as an intraocular filler to help retinal reposition. Its chemical stability ensures that it will not cause adverse reactions in the intraocular environment, and its good fluidity and optical properties can meet the requirements of surgery for visual clarity.
2. Multi-field penetration: At the same time, the application of medical silicone oil in dermatology, plastic surgery and other fields has gradually emerged. In dermatology, silicone oil is widely added to topical preparations for the treatment of dry skin, itching and other problems due to its good emollient and occlusive properties. It can form a protective film on the surface of the skin, reduce water evaporation, and promote the repair of skin barrier function. In plastic surgery, silicone oil is used for filling in breast augmentation, rhinoplasty and other surgeries, but due to insufficient understanding of its long-term safety in the early days, some complications occurred, which also prompted the scientific community to conduct more in-depth research on the safety assessment and quality control of medical silicone oil.
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